This post summarizes the identification of silylation artifacts from our laboratory and the literature. Normally silylation derivatization reactions give the desired derivative in high yields.
However, sometimes artifacts (by-products) are formed. The paper linked below lists all the types of artifacts noted in our laboratory in the last 20 years and ones we have found in the literature. It is a modified (not refereed) copy of a paper [J.L. Little, J. Chromatogr. A, 844 (1999) 1-22] containing additional examples found since the paper was published.