This posts describes techniques we find useful for the identification of a wide variety of surfactants in commercial products. More recently, I have found that accurate mass MS/MS data and molecular formulae searches in CAS can be very useful. Especially in you search one of the lower MW species in a PEG series using “Known Unknown” approach in SciFinder.
We originally developed many different techniques for the identification of surfactants in commercial latex plants. After we no longer needed the technology, I developed a course for PittCon and have included some links below:
List of Class Resources:
www.littledomain.com/pittcon.htm
Class Notes:
http://littledomain.com/james/files/pittcon/text.pdf
Class Powerpoint Presentation:
http://littledomain.com/james/files/pittcon/power_point.pdf
i want to know which LCMS will be better ion trap or triple quad for such identification
By: Dr. Subroto Das on April 10, 2012
at 8:30 am
Either would be fine. However, would prefer to have accurate mass data for identification of unknowns. Previously I had an LCT for doing accurate mass and obtained in-source CID spectra. However, currently have an Agilent QTOF and the MS/MS spectra much better for substructural information than the in-source CID.
By: tvasailor on April 10, 2012
at 12:48 pm